2 These four pea-sized glands produce parathyroid hormone, which helps maintain the right balance of calcium and phosphorus in your body. Parathyroid glandsДЄbout 95 percent of people with MEN1 develop tumors in the parathyroid glands by age 50. When small, these tumors may not cause any complications. Some tumors are nonfunctioning, which means they donвЂ™t produce hormones. whether or not the tumors are cancerous.In some cases, a large tumor may cause a gland to become underactive or unable to produce enough hormone. Although most of these tumors are noncancerous, they can cause the affected glands to increase in size and become overactive, producing too much hormone. MEN1 causes tumors to develop in endocrine glands and other parts of the body. What are the complications of having MEN1?

2,3 Most people are diagnosed as having MEN1 in their 40s, when the disorder has started to affect other endocrine glands. Although the disorder can affect all age groups, the first symptoms are typically linked to overactive parathyroid glands and often appear in people in their early 20s. If one of your parents has the gene for MEN1, you have a 50 percent chance of inheriting the defective gene. 1 Who is more likely to develop MEN1?ДЄ family history of the disorder increases your risk. MEN1 is a rare, inherited condition, occurring in about 1 in 30,000 people. Multiple tumors often develop at the same time in different tissues. People with MEN1 may also develop tumors-usually benign (not cancerous)-in other endocrine glands and body tissues, including the skin. pancreas and other parts of the digestive tract, such as the duodenum and stomach.Previously called WermerвЂ™s syndrome, MEN1 causes tumors to develop in the View full-sized image MEN1 can affect the parathyroids, pancreas, and pituitary glands. Located in different parts of the body, these glands control the production of hormones that direct many body processes, including growth, digestion, and sexual function. Multiple endocrine neoplasia type 1 (MEN1) is a rare genetic disorder that mainly affects the endocrine glands. What is multiple endocrine neoplasia type 1? What are the complications of having MEN1?.What is multiple endocrine neoplasia type 1?.

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